論文業績

2021年

  1. Yamamoto T, Kadoya H, Urabe E, Itano S, Sasaki T, Kashihara N：A rare case of amyloid light-chain amyloidosis with bilateral perirenal hematoma shortly after initiation of peritoneal dialysis. CEN Case Rep. 2021 Jan 7.
  2. Tokuyama A, Kanda E, Itano S, Kondo M, Wada Y, Kadoya H, Kidokoro K, Nagasu H, Sasaki T, Kashihara N：Effect of zinc deficiency on chronic kidney disease progression and effect modification by hypoalbuminemia. PLoS One. 2021 May 11;16(5):e0251554.
  3. Ohsawa R, Kadoya H, Obata A, Obata T, Tokuyama A, Sasaki T, Kashihara N, Kaneto H：Renal cell carcinoma sharply captured by imaging technology at an early stage in a hemodialysis patient: Usefulness of noninvasive monochrome superb microvascular imaging. Hemodial Int. 2021 Mar 29.
  4. Nishimura K, Taguchi K, Kishi S, Brooks CR, Ochi A, Kadoya H, Ikeda Y, Miyoshi M, Tamaki M, Abe H, Aihara KI, Kashihara N, Nagai K：Dual disruption of eNOS and ApoE gene accelerates kidney fibrosis and senescence after injury. Biochem Biophys Res Commun. 2021 Jun 4;556:142-148.
  5. Desposito D, Schiessl IM, Gyarmati G, Riquier-Brison A, Izuhara A, Kadoya H, Der B, Shroff UN, Hong YK, Peti-Peterdi J：Serial intravital imaging captures dynamic and functional endothelial remodeling with single-cell resolution. JCI Insight. 2021 Apr 13;123392.
  6. Tokuyama A, Kadoya H, Obata A, Obata T, Sasaki T, Kashihara N：Roxadustat and thyroid-stimulating hormone suppression. Clin Kidney J. 2021 Jan 20;14(5):1472-1474.
  7. Maruyama Y, Araki M, Kidokoro K, Sogawa Y, Yoshinaga K, Mitsui Y, Sadahira T, Wada K, Watanabe M, Watanabe T, Kashihara N, Nasu Y：Evaluation of Neutrophil Dynamics Change by Protective Effect of Tadalafil After Renal Ischemia/Reperfusion Using In Vivo Real-time Imaging. Transplantation.Apr 27,2021.
  8. Nishiwaki H, Niihata K, Shimizu S, Shibagak Y, Yamamoto R , Nitta K, Tsukamoto T, Uchida S, Takeda A,  Okada H, Narita I, Isaka Y, Kurita N : Japan Nephrotic Syndrome Cohort Study group：Incidence and factors associated with prescribing renin-angiotensin-system inhibitors in adult idiopathic nephrotic syndrome: A nationwide cohort study. J Clin Hypertens (Greenwich). 2021 May;23(5):999-1007.

2020年

  1. Kadoya H, Satoh M, Nishi Y, Kondo M, Wada Y, Sogawa Y, Kidokoro K, Nagasu H, Sasaki T, Kashihara N：Klotho is a novel therapeutic target in peritoneal fibrosis via Wnt signaling inhibition. Nephrol Dial Transplant. 2020 May 1;35(5):773-781.
  2. Nakagawa N, Sofue T, Kanda E, Nagasu H, Matsushita K, Nangaku M, Maruyama S, Wada T, Terada Y, Yamagata K, Narita I, Yanagita M, Sugiyama H, Shigematsu T, Ito T, Tamura K, Isaka Y, Okada H, Tsuruya K, Yokoyama H, Nakashima N, Kataoka H, Ohe K, Okada M, Kashihara N：J-CKD-DB: a nationwide multicentre electronic health record-based chronic kidney disease database in Japan. Sci Rep. 2020 Apr 30;10(1):7351.
  3. Sofue T, Nakagawa N, Kanda E, Nagasu H, Matsushita K, Nangaku M, Maruyama S, Wada T, Terada Y, Yamagata K, Narita I, Yanagita M, Sugiyama H, Shigematsu T, Ito T, Tamura K, Isaka Y, Okada H, Tsuruya K, Yokoyama H, Nakashima N, Kataoka H, Ohe K, Okada M, Kashihara N：Prevalences of hyperuricemia and electrolyte abnormalities in patients with chronic kidney disease in Japan: A nationwide, cross-sectional cohort study using data from the Japan Chronic Kidney Disease Database (J-CKD-DB). PLoS One. 2020 Oct 15;15(10):e0240402.
  4. Sofue T, Nakagawa N, Kanda E, Nagasu H, Matsushita K, Nangaku M, Maruyama S, Wada T, Terada Y, Yamagata K, Narita I, Yanagita M, Sugiyama H, Shigematsu T, Ito T, Tamura K, Isaka Y, Okada H, Tsuruya K, Yokoyama H, Nakashima N, Kataoka H, Ohe K, Okada M, Kashihara N：Prevalence of anemia in patients with chronic kidney disease in Japan: A nationwide, cross-sectional cohort study using data from the Japan Chronic Kidney Disease Database (J-CKD-DB). PLoS One. 2020 Jul 20;15(7):e0236132.
  5. Itano S, Yano Y, Nagasu H, Tomiyama H, Kanegae H, Makino H, Higashi Y, Kobayashi Y, Sogawa Y, Satoh M, Suzuki K, Raymond R.T, Matthew B, George B, and Kashihara N：Association of Arterial Stiffness With Kidney Function Among Adults Without Chronic Kidney Disease. Am J Hypertens. 2020 Nov 3;33(11):1003-1010.
  6. Sogawa Y, Kadoya H, Kashihara N：Drastic change in protein intake may cause a rapid decline of residual renal function after initiation of peritoneal dialysis. Ther Apher Dial. 2020 Dec;24(6):736-738.
  7. Itano S, Kadoya H, Satoh M, Nakamura T, Murase T, Sasaki T, Kanwar YS, Kashihara N：Non-purine selective xanthine oxidase inhibitor ameliorates glomerular endothelial injury in InsAkita diabetic mice. Am J Physiol Renal Physiol. 2020 Nov 1;319(5):F765-F772.
  8. Tang SCW, Yu X, Chen HC, Kashihara N, Park HC, Liew A, Goh BL, Nazareth MGC, Bunnag S, Tan J, Lun V, Lydia A, Sharma SK, Hoque E, Togtokh A, Ghnaimet M, Jha V：Dialysis Care and Dialysis Funding in Asia. Am J Kidney Dis. 2020 May;75(5):772-781.
  9. Ito S, Kashihara N, Shikata K, Nangaku M, Wada T, Okuda Y, Sawanobori T：Esaxerenone (CS-3150) in Patients with Type 2 Diabetes and Microalbuminuria (ESAX-DN): Phase 3 Randomized Controlled Clinical Trial. Clin J Am Soc Nephrol. 2020 Dec 7;15(12):1715-1727.
  10. Kashihara N, Yamasaki Y, Osonoi T, Harada H, Shibagaki Y, Zhao J, Kim H, Yajima T, Sarai N：A phase 3 multicenter open-label maintenance study to investigate the long-term safety of sodium zirconium cyclosilicate in Japanese subjects with hyperkalemia. Clin Exp Nephrol. 2021 Feb;25(2):140-149.
  11. Katsuno T, Ito Y, Kagami S, Kitamura H, Maruyama S, Shimizu A, Sugiyama H, Sato H, Yokoyama H, Kashihara N：A nationwide cross-sectional analysis of thrombotic microangiopathy in the Japan Renal Biopsy Registry (J-RBR). Clin Exp Nephrol. 2020 Sep;24(9):789-797.
  12. Yamamoto R, Imai E, Maruyama S, Yokoyama H, Sugiyama H, Nitta K, Tsukamoto T, Uchida S, Takeda A, Sato T, Wada T, Hayashi H, Akai Y, Fukunaga M, Tsuruya K, Masutani K, Konta T, Shoji T, Hiramatsu T, Goto S, Tamai H, Nishio S, Shirasaki A, Nagai K, Yamagata K, Hasegawa H, Yasuda H, Ichida S, Naruse T, Nishino T, Sobajima H, Tanaka S, Akahori T, Ito T, Terada Y, Katafuchi R, Fujimoto S, Okada H, Ishimura E, Kazama JJ, Hiromura K, Mimura T, Suzuki S, Saka Y, Sofue T, Suzuki Y, Shibagaki Y, Kitagawa K, Morozumi K, Fujita Y, Mizutani M, Shigematsu T, Kashihara N, Sato H, Matsuo S, Narita I, Isaka Y：Incidence of remission and relapse of proteinuria, end-stage kidney disease, mortality, and major outcomes in primary nephrotic syndrome: the Japan Nephrotic Syndrome Cohort Study (JNSCS). Clin Exp Nephrol. 2020 Jun;24(6):526-540.
  13. Kashihara N, Nishio T, Osonoi T, Saka Y, Imasawa T, Ohtake T, Mizuno H, Shibagaki Y, Kim H, Yajima T, Sarai N：Correction of serum potassium with sodium zirconium cyclosilicate in Japanese patients with hyperkalemia: a randomized, dose-response, phase 2/3 study. Clin Exp Nephrol. 2020 Dec;24(12):1144-1153.
  14. Yokoyama H, Yamamoto R, Imai E, Maruyama S, Sugiyama H, Nitta K, Tsukamoto T, Uchida S, Takeda A, Sato T, Wada T, Hayashi H, Akai Y, Fukunaga M, Tsuruya K, Masutani K, Konta T, Shoji T, Hiramatsu T, Goto S, Tamai H, Nishio S, Shirasaki A, Nagai K, Yamagata K, Hasegawa H, Yasuda H, Ichida S, Naruse T, Fukami K, Nishino T, Sobajima H, Tanaka S, Akahori T, Ito T, Terada Y, Katafuchi R, Fujimoto S, Okada H, Ishimura E, Kazama JJ, Hiromura K, Mimura T, Suzuki S, Saka Y, Sofue T, Suzuki Y, Shibagaki Y, Kitagawa K, Morozumi K, Fujita Y, Mizutani M, Shigematsu T, Furuichi K, Fujimoto K, Kashihara N, Sato H, Matsuo S, Narita I, Isaka Y：Better remission rates in elderly Japanese patients with primary membranous nephropathy in nationwide real-world practice: The Japan Nephrotic Syndrome Cohort Study (JNSCS). Clin Exp Nephrol. 2020 Oct;24(10):893-909.
  15. Bandaru S, Sano S, Shimizu Y, Seki Y, Okano Y, Sasaki T, Wada H, Otsuki T, Ito T：Impact of heavy rains of 2018 in western Japan: disaster-induced health outcomes among the population of Innoshima Island. Heliyon. 2020 May 25;6(5):e03942.
  16. Kadoya H, Yu　N, Schiessl IM, Riquier-Briston A, Gyarmati G, Desposito D, Kidokoro K, Butler MJ, Jacob CO, Peti-Peterdi J. ：Essential role and therapeutic targeting of the glomerular endothelial glycocalyx in lupus nephritis. JCI Insight. 2020 Oct 2;5(19):e131252.
  17. Yamaguchi R, Kawazoe Y, Shimamoto K, Shinohara E, Tsukamoto T, Shintani-Domoto Y, Nagasu H, Uozaki H, Ushiku T, Nangaku M, Kashihara N, Shimizu A, Nagata M, Ohe K：Glomerular Classification Using Convolutional Neural Networks Based on Defined Annotation Criteria and Concordance Evaluation Among Clinicians. JCI Insight. 2020 Oct 2;5(19):e131252.
  18. Kanda E, Kashihara N, Kohsaka S, Okami S, Yajima T：Clinical and Economic　Burden of Hyperkalemia: A Nationwide Hospital-Based Cohort Study in Japan. Kidney Med. 2020 Oct 17;2(6):742-752.e1.
  19. Wheeler DC, Stefansson BV, Batiushin M, Bilchenko O, Cherney DZI, Chertow GM, Douthat W, Dwyer JP, Escudero E, Pecoits-Filho R, Furuland H, Górriz JL, Greene T, Haller H, Hou FF, Kang SW, Isidto R, Khullar D, Mark PB, McMurray JJV, Kashihara N, Nowicki M, Persson F, Correa-Rotter R, Rossing P, Toto RD, Umanath K, Van Bui P, Wittmann I, Lindberg M, Sjöström CD, Langkilde AM, Heerspink HJL：The dapagliflozin and prevention of adverse outcomes in chronic kidney disease (DAPA-CKD) trial: baseline characteristics. Nephrol Dial Transplant. 2020 Oct 1;35(10):1700-1711.
  20. Heerspink HJL, Stefánsson BV, Correa-Rotter R, Chertow GM, Greene T, Hou FF, Mann JFE, McMurray JJV, Lindberg M, Rossing P, Sjöström CD, Toto RD, Langkilde AM, Wheeler DC; DAPA-CKD Trial Committees and Investigators：Dapagliflozin in Patients with Chronic Kidney Disease. N Engl J Med. 2020 Oct 8;383(15):1436-1446.
  21. Kanda E, Epureanu BI, Adachi T, Tsuruta Y, Kikuchi K, Kashihara N, Abe M, Masakane I, Nitta K：Application of explainable ensemble artificial intelligence model to categorization of hemodialysis-patient and treatment using nationwide-real-world data in Japan. PLoS One. 2020 May 29;15(5):e0233491.
  22. Kashihara N, Kidokoro K, Kanda E：Renoprotective effects of sodium-glucose cotransporter-2 inhibitors and underlying mechanisms. Curr Opin Nephrol Hypertens. 2020 Jan;29(1):112-118.
  23. Tang SCW, Yu X, Chen HC, Kashihara N, Park HC, Liew A, Goh BL, Nazareth MGC, Bunnag S, Tan J, Lun V, Lydia A, Sharma SK, Hoque E, Togtokh A, Ghnaimet M, Jha V：Dialysis Care and Dialysis Funding in Asia.  Am J Kidney Dis. 2020 May;75(5):772-781.

2019年

  1. Kidokoro K, Cherney D, Bozovic A, Nagasu H, Satoh M, Kanda E, Sasaki T, Kashihara N：Evaluation of Glomerular Hemodynamic Function by Empagliflozin in Diabetic Mice Using In Vivo Imaging. Circulation. 2019 Jul 23;140(4):303-315.
  2. Nagasu H, Sogawa Y, Kidokoro K, Itano S, Yamamoto T, Satoh M, Sasaki T, Suzuki T, Yamamoto M, Wigley W Christian, Proksch Joel W, Meyer Colin J, Kashihara N：Bardoxolone methyl analog attenuates proteinuria induced tubular damage by modulating mitochondrial function. FASEB J. 2019 Nov;33(11):12253-12263.
  3. Kashihara N, Kohsaka S, Kanda E, Okami S, Yajima T：Hyperkalemia in Real-World Patients Under Continuous Medical Care in Japan. Kidney Int Rep. 2019 May 30;4(9):1248-1260.
  4. Fukui A, Yokoo T, Nangaku M, Kashihara N：New measures against chronic kidney diseases in Japan since 2018.  Clin Exp Nephrol. 2019 Nov;23(11):1263-1271.
  5. Umemura S, Arima H, Arima S, Asayama K, Dohi Y, Hirooka Y, Horio T, Hoshide S, Ikeda S, Ishimitsu T, Ito M, Ito S, Iwashima Y, Kai H, Kamide K, Kanno Y, Kashihara N, Kawano Y, Kikuchi T, Kitamura K, Kitazono T, Kohara K, Kudo M, Kumagai H, Matsumura K, Matsuura H, Miura K, Mukoyama M, Nakamura S, Ohkubo T, Ohya Y, Okura T, Rakugi H, Saitoh S, Shibata H, Shimosawa T, Suzuki H, Takahashi S, Tamura K, Tomiyama H, Tsuchihashi T, Ueda S, Uehara Y, Urata H, Hirawa N：The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019).  Hypertens Res. 2019 Sep;42(9):1235-1481.
  6. Nakamura S, Hasebe N, Yatabe M, Kishi T, Ishida M, Ichihara A, Node K, Ishimitsu T, Itoh H, Ito M, Ohishi M, Ohkubo T, Kai H, Kashihara N, Kario K, Saitoh S, Tsuchihashi T, Nishiyama A, Higaki J, Miura K, Rakugi H, Kawano Y, Tamura K, Yatabe T, Ohya Y, Ito S：JSH Statement: Asahikawa declaration in promotion of diversity by the Japanese society of hypertension-the JSH Asahikawa declaration. Hypertens Res. 2019 Oct;42(10):1483-1484.
  7. Japanese Society of Nephrology (Kashihara N.)：Essential points from Evidence-based Clinical Practice Guidelines for Chronic Kidney Disease 2018. Clin Exp Nephrol. 2019 Jan;23(1):1-15.
  8. Nagasu A, Mukai T, Iseki M, Kawahara K, Tsuji S, Nagasu H, Ueki Y, Ishihara K, Kashihara N, Morita Y：Sh3bp2 Gain-Of-Function Mutation Ameliorates Lupus Phenotypes in B6.MRL-Faslpr Mice. Cells. 2019 Apr 30;8(5):402.
  9. Uchida A, Kidokoro K, Sogawa Y, Itano S, Nagasu H, Satoh M, Sasaki T, Kashihara N：5-Aminolevulinic acid exerts renoprotective effect via Nrf2 activation in murine rhabdomyolysis-induced acute kidney injury. Nephrology (Carlton). 2019 Jan;24(1):28-38.
  10. Satoh M, Maruhashi T, Yoshida Y, Shibata H：Systematic review of the clinical outcomes of mineralocorticoid receptor antagonist treatment versus adrenalectomy in patients with primary aldosteronis. Hypertens Res. 2019 Jun;42(6):817-824.
  11. Masaaki Ito, Toshihiko Ishimitsu, Atsuhiro Ichihara, Hiroshi Itoh, Mitsuru Ohishi, Takayoshi Ohkubo, Hisashi Kai, Naoki Kashihara, Kazuomi Kario, Shigeyuki Saitoh, Takuya Tsuchihashi, Satoko Nakamura, Akira Nishiyama, Koichi Node, Naoyuki Hasebe, Jitsuo Higaki, Katsuyuki Miura, Hiromi Rakugi, Kouichi Tamura, Yuhei Kawano, Takashi Yatabe, Yusuke Ohya & Sadayoshi Ito：JSH Statement: Kyoto declaration on hypertension research in Asia. Hypertens Res. 2019 Jun;42(6):759-760.
  12. Butler MJ, Ramnath R, Kadoya H, Desposito D, Riquier-Brison A, Ferguson JK, Onions KL, Ogier AS, ElHegni H, Coward RJ, Welsh GI, Foster RR, Peti-Peterdi J, Satchell SC：Aldosterone induces albuminuria via matrix metalloproteinase-dependent damage of the endothelial glycocalyx. Kidney Int. 2019 Jan;95(1):94-107.

受賞

2021年

第29回中国腎不全研究協会学術集会　優秀演題賞　高須　将伸
川崎医科大学附属病院　病院長より　感謝状　長洲　一
川崎医科大学附属病院　病院長より　感謝状　城所　研吾
日本透析医学会奨励賞　角谷　裕之

2020年

The 9th chronic kidney disease CKD Frontier Award　 徳山　敦之
公益財団法人ウエスコ学術振興財団　2020年度学術研究費助成金　　角谷　裕之
公益財団法人川崎医学・医療福祉学振興会　教育研究助成金　和田　佳久
第63回日本腎臓学会学術総会　優秀演題賞　角谷　裕之
川崎医科大学附属病院卒後臨床研修　ベスト指導医　山内　祐
Okayama Prefectural Medical Association　Academic Award 2020　角谷　裕之

2019年

一般財団法人日本健康増進財団H30年度「生活習慣予防等に関する研究助成金」　板野　精之
第23 回(2019年度) 日本心血管内分泌代謝学会　高峰譲吉賞 　柏原　直樹
第120回日本内科学会中国地方会 奨励賞　　卜部　恵莉子
公益財団法人ウエスコ学術振興財団2019年度学術研究費助成金　　城所　研吾
公益財団法人川崎医学・医療福祉学振興会　教育研究助成金　　十川　裕史
公益財団法人大樹生命厚生財団　第52回医学研究助成　　長洲　一
令和元年度　川崎医科大学学術集会　優秀ポスター発表賞　　板野　精之
第25回日本腹膜透析医学会学術集会・総会　優秀演題賞　　角谷　裕之