1. Colchicine attenuates renal fibrosis in a murine unilateral ureteral obstruction model. Mol Med Rep. 15(6):4169-75, 2017
  2. Nishimura H, Yaoita E, Nameta M, Yamaguchi K, Sato M, Ihoriya C, Zhao L, Kawachi H, Sasaki T, Ikezumi Y, Ouchi Y, Kashihara N, Yamamoto T. Restricted nutrition-induced low birth weight, low number of nephrons and glomerular mesangium injury in Japanese quail. J Dev Orig Health Dis. 8(3):287-300, 2017
  3. Tomita J, Mochizuki S, Fujimoto S, Kashihara N, Akasaka T, Tanimoto M, Yoshida K. Acute improvement of endothelial functions after oral ingestion of isohumulones, bitter components of beer. Biochem Biophys Res Commun. 484(4):740-5, 2017
  4. Nakamura K, Miura D, Saito Y, Yunoki K, Koyama Y, Satoh M, Kondo M, Osawa K, Hatipoglu OF, Miyoshi T, Yoshida M, Morita H, Ito H. Eicosapentaenoic acid prevents arterial calcification in klotho mutant mice.PLoS One.12(8);e0181009, 2017
  5. Sogawa Y, Nagasu H, Iwase S, Ihoriya C, Itano S, Uchida A, Kidokoro K, Taniguchi S, Takahashi M, Satoh M, Sasaki T, Suzuki T, Yamamoto M, Horng T, Kashihara N. Infiltration of M1, but not M2, macrophages is impaired after unilateral ureter obstruction in Nrf2-deficient mice. Sci Rep.7(1);8801,2017


  1. Nagasu H, Satoh M, Kiyokage E, Kidokoro K, Toida K, Channon KM, Kanwar YS, Sasaki T, Kashihara N. Activation of endothelial NAD(P)H oxidase accelerates early glomerular injury in diabetic mice. Lab Invest. 96(1):25-36, 2016
  2. Namikoshi T, Harada K, Hatta H, Tokura T, Oshiro Y, Nishizaki T, Obata T, Mori M, Fueki T, Fujimoto S, Haruna Y, Kuwabara A, Yorimitsu D, Ihoriya C, Kadoya H, Itano S, Fujimoto Y, Komai N, Sasaki T, Kashihara N. Prevalence of gastroesophageal reflux disease symptoms and effects of esomeprazole on the quality of life related to reflux and dyspepsia in patients on maintenance hemodialysis.Clin Exp Nephrol.20(1):134-42, 2016
  3. Kidokoro K, Satoh M, Itano S, Kuwabara A, Sasaki T, Kashihara N. Feasibility of fluorescence energy transfer system for imaging the renoprotective effects of aliskiren in diabetic mice.
    J Renin Angiotensin Aldosterone Syst. 17(2): on line, 2016
  4. Kadoya H, Uchida A, Kashihara N. A case of copper deficiency-induced pancytopenia with maintenance hemodialysis outpatient treated with polaprezinc. Ther Apher Dial. 20(4):422-3, 2016
  5. Kadoya H, Satoh M, Haruna Y, Sasaki T, Kashihara N. Klotho attenuates renal hypertrophy and glomerular injury in Ins2Akita diabetic mice. Clin Exp Nephrol. 20(5):671-8, 2016
  6. Oyama J, Murohara T, Kitakaze M, Ishizu T, Sato Y, Kitagawa K, Kamiya H, Ajioka M, Ishihara M, Dai K, Nanasato M, Sata M, Maemura K, Tomiyama H, Higashi Y, Kaku K, Yamada H, Matsuhisa M, Yamashita K, Bando YK, Kashihara N, Ueda S, Inoue T, Tanaka A, Node K; PROLOGUE Study Investigators. The Effect of Sitagliptin on Carotid Artery Atherosclerosis in Type 2 Diabetes: The PROLOGUE Randomized Controlled Trial. PLoS Med. 13(6):e1002051, 2016


  1. Satoh M, Nishi Y, Kadoya H, Itano S, Komai N, Sasaki T, Kashihara N. Combination Irbesartan/Amlodipine versus Irbesartan/Cilnidipine for Attenuation of Albuminuria in Rats with Streptozotocin-Induced Diabetic Nephropathy. Pharm Anal Acta. 6(5):369, 2015
  2. Kadoya H, Satoh M, Nagasu H, Sasaki T, Kashihara N.Deficiency of endothelial nitric oxide signaling pathway exacerbates peritoneal fibrosis in mice. Clin Exp Nephrol.19(4):567-75, 2015
  3. Namikoshi T, Fujimoto S, Yorimitsu D, Ihoriya C, Fujimoto Y, Komai N, Sasaki T, Kashihara N. Relationship between vascular function indexes, renal arteriolosclerosis, and renal clinical outcomes in chronic kidney disease. Nephrology (Carlton). 20(9):585-90, 2015
  4. Kadoya H, Satoh M, Sasaki T, Taniguchi S, Takahashi M, Kashihara N. Excess aldosterone is a critical danger signal for inflammasome activation in the development of renal fibrosis in mice. FASEB J. 29(9):3899-910, 2015
  5. Yorimitsu D, Sasaki T, Horike H, Fueki T, Hujimoto S, Komai N, Satoh M, Kashihara N. Severe hyperkalemia following ileostomy not colostomy in a patient undergoing chronic hemodialysis. Kawasaki Med J. 41(2):65-69, 2015


  1. Ihoriya C, Satoh M, Kuwabara A, Sasaki T, Kashihara N. Angiotensin II Regulates Islet Microcirculation and Insulin Secretion in Mice.Microcirculation. 21(2):112-23, 2014
  2. Satoh M, Nagasu H, Haruna Y, Ihoriya C, Kadoya H, Sasaki T, Kashihara N. Hypertension promotes islet morphological changes with vascular injury on pre-diabetic status in SHRsp rats. Clin Exp Hypertens. 36(3):159-164, 2014
  3. Ihoriya C, Satoh M, Komai N, Sasaki T, Kashihara N. Nuclear factor erythroid 2-related factor 2 is activated by rosuvastatin via p21cip1 upregulation in endothelial cells. Biochem Pharmacol (Los Angel). 4(1):157, 2014


  1. Angiostatin production increases in response to decreased nitric oxide in aging rat kidney. Lab Invest. 93(3):334-43,2013
  2. Nishi Y, Satoh M, Nagasu H, Kadoya H, Ihoriya C, Kidokoro K, Sasaki T, Kashihara N. Selective estrogen receptor modulation attenuates proteinuria-induced renal tubular damage by modulating mitochondrial oxidative status. Kidney Int. 83(4):662-73,2013
  3. Satoh M, Ueta H, Tokura T, Sasaki T, Kashihara N. Erythropoietin-producing tubercle granuloma in a hemodialysis patient. BMC Nephrol. 14(1):91,2013
  4. Kidokoro K, Satoh M, Channon KM, Yada T, Sasaki T, Kashihara N. Maintenance of Endothelial Guanosine Triphosphate Cyclohydrolase I Ameliorates Diabetic Nephropathy.J Am Soc Nephrol. 24(7):1139-50,2013


  1. Nagasu H, Satoh M, Fujimoto S, Tomita N, Sasaki T, Kashihara N. Azelnidipine attenuates glomerular damage in Dahl salt-sensitive rats by suppressing sympathetic nerve activity. Hypertens Res. 35(3):348-55,2012
  2. Nagasu H, Satoh M, Kidokoro K, Nishi Y, Channon KM, Sasaki T, Kashihara N. Endothelial dysfunction promotes the transition from compensatory renal hypertrophy to kidney injury after unilateral nephrectomy in mice. Am J Physiol Renal Physiol. 302(11):F1402-8,2012
  3. Kidokoro K, Satoh M, Nagasu H, Sakuta T, Kuwabara A, Yorimitsu D, Nishi Y, Tomita N, Sasaki T, Kashihara N. Tacrolimus induces glomerular injury via endothelial dysfunction caused by reactive oxygen species and inflammatory change. Kidney Blood Press Res. 35(6):549-57,2012
  4. Yorimitsu D, Satoh M, Koremoto M, Haruna Y, Nagasu H, Kuwabara A, Sasaki T, Kashihara N. Establishment of a blood purification system for renal failure rats using small-size dialyzer membranes. Ther Apher Dial. 16(6):566-72,2012
  5. Satoh M, Nagasu H, MoritaY, Yamaguchi TP, Kanwar YS, Kashihara N. Klotho protects against mouse renal fibrosis by inhibiting Wnt signaling.Am J Physiol Renal Physiol. 303(12):F1641-51,2012


  1. Nagasu H, Satoh M, Yorimitsu D, Tomita N, Sasaki T, Kashihara N. Comparison of Combination Therapy of Olmesartan plus Azelnidipine or Hydrochlorothiazide on Renal and Vascular Damage in SHR/NDmcr-cp Rats.Kidney Blood Press Res. 34(2):87-96,2011
  2. Satoh M, Fujimoto S, Horike H, Ozeki M, Nagasu H, Tomita N, Sasaki T, Kashihara N. Mitochondrial damage-induced impairment of angiogenesis in the aging rat kidney. Lab Invest. 91(2):190-202,2011
  3. Nagasu H, Satoh M, Kuwabara A, Yorimitsu D, Kidokoro K, Nishi Y, Tomita N, Sasaki T, Kashihara N. Overexpression of klotho protein modulates uninephrectomy-induced compensatory renal hypertrophy by suppressing IGF-I signals. Biochem Biophys Res Commun. 407(1):39-43,2011
  4. Tokura T, Itano S, Kobayashi S, Kuwabara A, Fujimoto S, Horike H, Satoh M, Komai N, Tomita N, Matsunaga A, Saito T,  Sasaki T, Kashihara N. A Novel Mutation ApoE2 Kurashiki (R158P) in a Patient with Lipoprotein Glomerulopathy. J Atheroscler Thromb. 18(6):536-41,2011


  1. Telmisartan improves endothelial dysfunction and renal autoregulation in Dahl salt-sensitive rats. Hypertens Res. 33(2):135-42,2010
  2. Satoh M, Kobayashi S, Kuwabara A, Tomita N, Sasaki T, Kashihara N. In vivo visualization of glomerular microcirculation and hyperfiltration in streptozotocin-induced diabetic rats.
  3. Nagasu H, Satoh M, Kuwabara A, Yorimitsu D, Sakuta T, Tomita N, Kashihara N. Renal denervation reduces glomerular injury by suppressing NAD(P)H oxidase activity in Dahl salt-sensitive rats. Nephrol Dial Transplant. 25(9):2889-98,2010
  4. Sakuta T, Morita Y, Satoh M, David A. Fox, Kashihara N. Involvment of the renin-angiotensin system in the development of vascular damage in a rat model of arthritis. Arthritis Rheum. 62(5):1319-28,2010
  5. Mochizuki S, Takayama A, Sasaki T, Yada T, Endo K, Horike H, Kashihara N, Ogasawara Y, Kajiya F. Clear correlation of tetrahydrobiopterin with nitric oxide bioavailability in continuous ambulatory peritoneal dialysis. Blood Purif. 30(2):96-7, 2010
  6. Kuwabara A, Satoh M, Tomita N, Sasaki T, Kashihara N. Deterioration of glomerular endothelial surface layer induced by oxidative stress is implicated in altered permeability of macromolecules in Zucker fatty rats. Diabetologia. 53(9):2056-65,2010
  7. Nishi Y, Namikoshi T, Sasaki T, Tokura T, Nagasu H, Nakanishi H, Kozuka Y, Kashihara N. Histopathological manifestations of membranoproliferative glomerulonephritis and glomerular expression of plasmalemmal vesicle-associated protein-1 in a patient with polycythemia vera. Clinical Nephrology. 74(5):393-8,2010